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KMID : 0378020070500010038
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New Medical Journal
2007 Volume.50 No. 1 p.38 ~ p.44
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Therapeutic efficacy and safety of ultrasound-guided percutaneous needle aspiration/catheter drainage of fluid collections or abscesses in patients with hematological malignancy
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Lee Sang-Hoon
Choi Byung-Gil
Hahn Seong-Tai
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Abstract
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Background: The purpose of this study is to evaluate the efficacy and safety of ultrasoundguided percutaneous drainage of fluid collections or abscesses in severely immunecompromised patients caused by hematological malignancies.
Material and Methods : From March 2001 to December 2004, ultrasound-guided percutaneous drainage of abscesses or fluid collections was performed in 36 patients (male; 24, female; 12) with hematological malignancies. Their age was 14 to 57 years old (mean; 39.3 years). The drainage was performed for the treatment of abscess (n=15), pleural effusion (n=19), and ascites (n=2).
The technical success rate, symptomatic improvement, duration of catheter drainage, and the relationship between laboratory results and complications were analyzed.
Results: Aspiration/Drainage was successful in 35 patients, and in the other 1 patient, combined ultrasound and CT-guided approach was required. There were no complications associated with procedure. Symptomatic improvement was noted in 27 patients. The mean duration of drainage was 6.6 days (range; 1-25 days), and the catheter was removed due to dislodgement (n=1), drainage catheter insertion site infection (n=1), and clinically septic condition (n=1). One of 8 patients who had severe neutropenia showed infectious complication. Five of 15 patients who had abnormal coagulation parameters showed hemorrhage around drainage catheter insertion site, however, they were improved by the transfusion and manual compression of the catheter insertion site.
Conclusion: Ultrasound-guided percutaneous drainage of fluid collections or abscess in patients with hematological malignancies is effective and safe method with few life-threatening infectious or hemorrhagic complications.
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KEYWORD
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Ultrasound (US), Abscess, Percutaneous drainage, Leukemia, Complications
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